Abstract: Eyelid pilomatricoma is a benign tumor originating from the stromal cells of the skin follicle and presents primarily as a painless, firm lump, typically composed of basophils cells, shadow cells and transitional cells. The clinical presentation is complex and variable, and the rate of misdiagnosis is relatively high. It is important to note that this disease needs to be distinguished from sebaceous cysts and eyelid hemangiomas from each other. Ultrasound examination is an important method for diagnosing this disease, and histopathology is the "gold standard" for diagnosing this disease. The treatment is mainly surgical resection with a good postoperative prognosis,and optimal treatment has not been found. (Int Rev Ophthalmol, 2022, 46:  571-576)

Key words: eyelid, pilomatricoma